L.YangP
DOI:10.29169/1927-5951.2024.14.01
Additionally, it has been demonstrated that the combination of docetaxel and R162 inhibits the development and metastasis of non-small cell lung cancer cells resistant to docetaxel, hence bolstering the effectiveness of combination therapy including anticancer medications and GLUD1 inhibitors as a cancer treatment approach [111]
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Thus, the effects observed here may extend beyond solid organ transplantation and could be relevant to other clinical settings associated with a high risk of acute kidney injury and exposure to high-dose glucocorticoids, including severe systemic inflammatory states (e.g., for COVID19 pneumonia [31])
In the case of this medication, which is typical of any antibiotic, by using it we are literally destroying not just the over-represented bacteria but impacting the entire microbiome negatively